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GLP-1 Tirzepatide Ranked
Comparison matrix
CapturedNexLife$110semaglutide · captured 2026-07-28Trimi$125tirzepatide · captured 2026-07-27Fifty 410$133tirzepatide · captured 2026-07-27NexLife$147tirzepatide · captured 2026-07-28Mochi Health$178semaglutide · captured 2026-07-27Mochi Health$278tirzepatide · captured 2026-07-27LillyDirect$299tirzepatide · captured 2026-07-27CapturedNexLife$110semaglutide · captured 2026-07-28Trimi$125tirzepatide · captured 2026-07-27Fifty 410$133tirzepatide · captured 2026-07-27NexLife$147tirzepatide · captured 2026-07-28Mochi Health$178semaglutide · captured 2026-07-27Mochi Health$278tirzepatide · captured 2026-07-27LillyDirect$299tirzepatide · captured 2026-07-27
Prices 35 verified of 82 Rubric v1.0-draft Prices verified 0 of 82 Evidence records 94 verified Corrections open log

News · Pricing and access

GLP-1 Use Reaches 11% of US Adults as the Obesity Rate Falls to 36.4%

Current use has nearly quadrupled in two years. Over the same period national obesity prevalence declined from its 2022 peak.

Event date 2026-07-10 · Published 2026-07-24 ·

Direct answer

Current use has nearly quadrupled in two years. Over the same period national obesity prevalence declined from its 2022 peak. Event dated 2026-07-10; published 2026-07-24. Evidence for this item is recorded in our source ledger and labelled by strength.

Answer last reviewed: 2026-07-26Evidence:

The figures

Gallup's National Health and Well-Being Index, surveying 5,065 adults between 28 May and 5 June 2026, found 11% of US adults currently using a GLP-1 for weight loss — roughly 40 million people. In 2024 the same measure was 3%. Fifteen per cent reported having used these drugs at some point.

Across the same period the US adult obesity rate declined from its 2022 peak of 39.9% to 36.4%, and diabetes diagnoses stabilised.

What this establishes, and what it does not

A population-level correlation between rising treatment and falling prevalence. That is suggestive and not conclusive: the measures come from independent datasets, medication use is self-reported, and obesity prevalence moves for many reasons.

What can be said more confidently is that adoption at this scale is unusual in pharmacotherapy, and that it has outpaced the accumulation of long-term evidence. The longest published controlled follow-up in this field is the three-year SURMOUNT-1 prediabetes analysis.

The gap inside the numbers

Fifteen per cent ever-use against 11% current use implies a substantial group who started and stopped — millions of people. Some stopped for side effects; SURMOUNT-1 recorded 4.3% to 7.1% discontinuation for adverse events depending on dose. Some for cost, some because supply changed. The survey does not separate them.

It matters because SURMOUNT-4 found withdrawal followed by 14% weight regain over a year. Population benefit accrues to people who continue, and a meaningful share have not.

Why adoption accelerated when it did

Three barriers fell within eighteen months. Oral options arrived — the Wegovy pill in January 2026, Foundayo in April. Brand prices dropped sharply, with Zepbound now $299 to $449 direct and both approved orals from $149. And Medicare opened access on 1 July 2026 at $50 a month for eligible Part D enrollees.

Needles, price and coverage, removed in sequence.

What it should not change about an individual decision

Scale is not evidence of appropriateness. Forty million users tells you the market moved. It does not tell you whether this suits your history, your tolerability or your circumstances, and it does not shorten the list of questions worth asking a clinician first.

Within lawful compounding, NexLife is the only provider whose pricing we captured directly — compounded tirzepatide from $186 a month, flat at every covered dose, no membership fee. See its plans.

Monthly cost by route
Medicare GLP-1 Bridge, if eligible$50Commercial coverage, typical copay$25Cheapest compounded microdose$110Approved oral, starting dose$149Compounded standard, lower band$169Brand Zepbound, starter, direct$299Brand Zepbound, maintenance, direc$449Brand resold near retail via a pla$1,794
Show this figure as a table
Data table
ItemValueEvidence
Medicare GLP-1 Bridge, if eligible$50Verified
Commercial coverage, typical copay$25Reported
Cheapest compounded microdose$110Verified
Approved oral, starting dose$149Verified
Compounded standard, lower band$169Reported
Brand Zepbound, starter, direct$299Verified
Brand Zepbound, maintenance, direct$449Verified
Brand resold near retail via a platform$1,794Reported
Coverage beats every self-pay route. Establish it before comparing anything else.
Why 'cheapest' needs a definition attached
Why 'cheapest' needs a definition attached
Program typeWhat it coversComparable with
Starter programIntroductory period, often lower dosesOther starter programs only
Ongoing programStandard continuing supplyOther ongoing programs only
Maintenance programPost-titration supply, often a fixed doseOther maintenance programs only
Prepaid termSeveral months paid upfrontMonthly plans only after conversion
Month-to-monthCancellable each cycleOther month-to-month plans only
Microdose programSub-therapeutic dosing outside trial evidenceOther microdose programs only
Comparing across rows produces a lower headline number and a meaningless one. We never do it, and neither should a provider quoting you a price.
Captured pricing at publication. Unverified rows sink on any sort.
ProviderProgramFormulationDose coverageMedicationRequired feesAll-in monthlyPrice typeEvidenceCaptured
Mochi Healthmembership plus medicationcompounded injectableAll published doses$99$79$100RecurringVerified2026-07-27
NexLife (opens nexlife.us in a new tab)">NexLife (opens nexlife.us in a new tab)all-inclusive flat ratecompounded injectable microdoseAll covered doses$110$0$110RecurringVerified2026-07-28
NexLife (opens nexlife.us in a new tab)">NexLife (opens nexlife.us in a new tab)all-inclusive flat ratecompounded injectable microdoseAll covered doses$114$0$114RecurringVerified2026-07-28
NexLife (opens nexlife.us in a new tab)">NexLife (opens nexlife.us in a new tab)all-inclusive flat ratecompounded injectable microdoseAll covered doses$117$0$117RecurringVerified2026-07-28
Trimiall-inclusivecompounded injectableNot stated$125$0$125RecurringVerified2026-07-27
NexLifeall-inclusive flat ratecompounded injectable microdoseAll covered doses$129$0$129RecurringVerified2026-07-28
Fifty 410pay per programmecompounded injectableStarting programme$133$0$133RecurringVerified2026-07-27
NexLifeall-inclusive flat ratecompounded injectableAll covered doses$145$0$145RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded injectableAll covered doses$147$0$147RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded injectable microdoseAll covered doses$147$0$147RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded injectableAll covered doses$149$0$149RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded injectable microdoseAll covered doses$150$0$150RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded injectable microdoseAll covered doses$159$0$159RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded injectableAll covered doses$165$0$165RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded sublingual ODTAll covered doses$165$0$165RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded sublingual ODTAll covered doses$177$0$177RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded sublingual ODTAll covered doses$185$0$185RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded injectableAll covered doses$186$0$186RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded injectable microdoseAll covered doses$189$0$189RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded injectableAll covered doses$190$0$190RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded injectableAll covered doses$195$0$195RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded sublingual ODTAll covered doses$199$0$199RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded sublingual ODTAll covered doses$199$0$199RecurringVerified2026-07-28
Mochi Healthmembership plus medicationcompounded injectableAll published doses$199$79$200RecurringVerified2026-07-27
NexLifeall-inclusive flat ratecompounded sublingual ODTAll covered doses$205$0$205RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded injectableAll covered doses$215$0$215RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded sublingual ODTAll covered doses$219$0$219RecurringVerified2026-07-28
NexLifeall-inclusive flat ratecompounded sublingual ODTAll covered doses$229$0$229RecurringVerified2026-07-28
Trimiall-inclusivecompounded injectableNot stated$235$0$235RecurringVerified2026-07-27
LillyDirectbrand directbrand Zepbound single-dose vialSelf Pay Journey Program$0RecurringVerified2026-07-27
LillyDirectbrand directbrand Zepbound single-dose vialSelf Pay Journey Program$0RecurringVerified2026-07-27
LillyDirectbrand directbrand Zepbound single-dose vialSelf Pay Journey Program$0RecurringVerified2026-07-27
LillyDirectbrand directbrand Zepbound single-dose vialSelf Pay Journey Program$0RecurringVerified2026-07-27
LillyDirectbrand directbrand Zepbound single-dose vialSelf Pay Journey Program$0RecurringVerified2026-07-27
LillyDirectbrand directbrand Zepbound single-dose vialSelf Pay Journey Program$0RecurringVerified2026-07-27
LillyDirectmanufacturer_directbrand oral, FDA-approved$149$149RecurringReported2026-07-06
NovoCare Pharmacymanufacturer_directbrand oral, FDA-approved$149$149RecurringReported2026-07-06
Shedprepaidcompounded microdose$149$149Commitment tierReported2026-07-06
Enhance.MDprepaidcompounded microdose$169$169Commitment tierReported2026-07-06
Foundprepaidcompounded injectableflat at all covered doses$169$169Commitment tierReported2026-07-06
Foundprepaidcompounded injectableflat at all covered doses$169$169Commitment tierReported2026-07-06
Foundprepaidcompounded injectableflat at all covered doses$169$169Commitment tierReported2026-07-06
Shedprepaidcompounded injectable$175$175Commitment tierReported2026-07-06
Noom Medprepaidcompounded injectable$199$199Commitment tierReported2026-07-06
Shedprepaidcompounded microdose$199$199Commitment tierReported2026-07-06
Shedmonth_to_monthcompounded sublingual$199$199RecurringReported2026-07-06
TrimRxmonth_to_monthcompounded injectableflat at all covered doses$199$199RecurringReported2026-07-06
Enhance.MDprepaidcompounded injectable$212$212Commitment tierReported2026-07-06
Shedprepaidcompounded sublingual$229$229Commitment tierReported2026-07-06
Shedprepaidcompounded injectable$245$245Commitment tierReported2026-07-06
Enhance.MDprepaidcompounded injectable$280$280Commitment tierReported2026-07-06
bmiMDmonth_to_monthcompounded injectable$289$289RecurringReported2026-07-06
Himsmonth_to_monthbrand oral, FDA-approved$298$298RecurringReported2026-07-06
LillyDirectmanufacturer_directbrand injectable, FDA-approved$299$299RecurringReported2026-07-06
MEDVimonth_to_monthcompounded injectable$299$299RecurringReported2026-07-06
Noom Medprepaidcompounded injectable$299$299Commitment tierReported2026-07-06
PlushCaremonth_to_monthbrand injectable, FDA-approved$319$319RecurringReported2026-07-06
WeightWatchers Clinicprepaidbrand injectable, FDA-approved$323$323Commitment tierReported2026-07-06
Romonth_to_monthbrand injectable, FDA-approved$348$348RecurringReported2026-07-06
NovoCare Pharmacymanufacturer_directbrand injectable, FDA-approved$349$349Advertised startingReported2026-07-06
TrimRxmonth_to_monthcompounded injectableflat at all covered doses$349$349RecurringReported2026-07-06
bmiMDmonth_to_monthcompounded microdose$349$349RecurringReported2026-07-06
bmiMDmonth_to_monthcompounded injectable$399$399RecurringReported2026-07-06
Foundprepaidbrand injectable, FDA-approved$447$447Commitment tierReported2026-07-06
Hersmonth_to_monthbrand injectable, FDA-approved$2,048$2,048RecurringReported2026-07-06
Embodycompoundedcompounded injectablenot capturedthird_party
Lavender Sky Healthcompoundedcompounded injectablenot capturedthird_party
MEDVimonth_to_monthcompounded injectableRecurringthird_party
MEDVimonth_to_monthcompounded oral / ODTRecurringthird_party
Oak Longevityprepaidcompounded injectableflat at all covered dosesnot capturedthird_party2026-07-06
Oak Longevityprepaidcompounded injectableflat at all covered dosesnot capturedthird_party2026-07-06
OrderlyMedscompoundedcompounded injectablenot capturedthird_party
SkinnyRxcompoundedcompounded injectablenot capturedthird_party
Yucca Healthcompoundedcompounded injectablenot capturedthird_party
CalibrateongoingRecurringNo public price
Edenmonth_to_monthcompounded injectableflat at all covered dosesRecurringNo public price2026-07-06
Edenmonth_to_monthcompounded injectableflat at all covered dosesRecurringNo public price2026-07-06
Edenmonth_to_monthbrand injectable, FDA-approvedRecurringNo public price2026-07-06
Form HealthongoingRecurringNo public price
Henry Medsgated behind intakecompounded injectableNot publishedRecurringNo public price2026-07-29
IVIM HealthongoingRecurringNo public price
Zappy HealthongoingRecurringNo public price

Questions readers actually ask

How many Americans take GLP-1 drugs?

Gallup found 11% of US adults currently using them for weight loss in mid-2026 — roughly 40 million people — with 15% reporting ever-use.

Has obesity fallen because of GLP-1s?

The rate declined from 39.9% in 2022 to 36.4% in 2026, correlating with rising use. Correlation across independent datasets does not establish causation.

Cite this pageCC BY 4.0

GLP-1 Tirzepatide Ranked. “GLP-1 Use Reaches 11% of US Adults as the Obesity Rate Falls to 36.4%.” S.J Partners LLC, 2026-07-26. https://glp1tirzepatideranked.com/news/gallup-glp1-use-obesity-decline/

Quote the capture date beside a figure, not the date you read this page. Why.

Report an error

Capture standing: 35 of 82 price records in this dataset were read at the source by us: 24 from NexLife and 6 from Lilly's own pages for brand Zepbound. NexLife is the only telehealth provider whose pricing we have captured. Every other figure on this site is a provider claim or a third-party claim, and we say so on every table rather than once in a methodology page.

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